diff --git a/tox.ini b/tox.ini
index d5b41af..972c05e 100644
--- a/tox.ini
+++ b/tox.ini
@@ -301,6 +301,18 @@
     find . -type f -name "*.pyc" -delete
     tempest run --regex {[testenv:slow]regex} {posargs}
 
+[testenv:multinode]
+envdir = .tox/tempest
+sitepackages = {[tempestenv]sitepackages}
+basepython = {[tempestenv]basepython}
+setenv = {[tempestenv]setenv}
+deps = {[tempestenv]deps}
+# The regex below is used to select the multinode and smoke tagged tests
+regex = '\[.*\bsmoke|multinode\b.*\]'
+commands =
+    find . -type f -name "*.pyc" -delete
+    tempest run --regex {[testenv:multinode]regex} {posargs}
+
 [testenv:ipv6-only]
 envdir = .tox/tempest
 sitepackages = {[tempestenv]sitepackages}